Regenerative Skin

Polynucleotides

A treatment for clients who want gradual skin improvement without adding volume or changing facial structure.

The Intention

Polynucleotides are used to improve skin quality by supporting the skin’s natural repair processes. They are not designed to add volume or change the shape of the face.

The focus is on improving the appearance of tired, thin, crepey, dehydrated, or ageing skin over time.

This treatment is suitable for clients who want healthier-looking skin, better elasticity, and a more refreshed appearance through a regenerative approach.

What Are Polynucleotides?

Polynucleotides are injectable regenerative skin treatments used to support tissue repair, hydration, elasticity, and overall skin resilience.

They work gradually by supporting the skin environment and encouraging improved skin quality over time. Results develop progressively rather than instantly.

At Maison Nēphèiä, polynucleotides are used as part of a skin-focused treatment plan for clients who want natural-looking improvement without an overfilled or artificial result.

The Maison Approach

Treatment begins with a consultation and skin assessment. Areas of concern are reviewed, including skin texture, hydration, elasticity, fine lines, crepiness, and overall skin quality.

Polynucleotides are placed carefully into the skin using a series of precise injections. The treatment plan may focus on one area or form part of a wider regenerative skin plan.

A course is usually recommended for best results, followed by maintenance depending on your skin condition, goals, and response to treatment.

Benefits

• Improves the appearance of fine lines and crepey skin
• Supports collagen and elastin activity
• Helps improve firmness, elasticity, and hydration
• Supports skin repair and resilience
• Can improve the look of tired or dull skin
• Suitable for delicate areas including the under-eyes, neck, and décolleté
• Works well as part of a long-term skin quality plan

Who It Is For

Polynucleotides may be suitable for clients who want to improve skin quality without adding volume.

• Fine lines or early signs of ageing
• Thin, crepey, or tired-looking skin
• Loss of elasticity or firmness
• Dehydrated or dull skin
• Under-eye skin quality concerns
• Neck or décolleté crepiness
• Clients who prefer gradual regenerative improvement

Areas That Can Be Treated

• Under-eyes
• Face
• Neck
• Décolleté
• Hands
• Other areas may be assessed during consultation

Results and Longevity

Results develop gradually over several weeks as the skin begins to look smoother, firmer, more hydrated, and more resilient.

A course of treatment is usually recommended, often spaced several weeks apart. The exact number of sessions will depend on your skin condition, treatment area, and desired result.

Results may last around 6–12 months depending on the individual, lifestyle, skin quality, and maintenance plan.

Pre-Care

Before your appointment, you may be advised to avoid alcohol, intense exercise, and blood-thinning medication where medically safe to do so.

Please arrive with clean skin where possible and inform the clinic of any medication, allergies, active skin conditions, pregnancy, breastfeeding, or recent aesthetic treatments.

Aftercare

Mild redness, swelling, tenderness, bruising, or pinpoint marks can occur after treatment and usually settle within a few days.

• Avoid touching or massaging the treated area unless advised
• Avoid makeup for the recommended period after treatment
• Avoid intense exercise, heat, sauna, steam, and sunbeds for 24–48 hours
• Use gentle skincare and avoid strong actives until the skin has settled
• Apply SPF daily and follow your aftercare instructions carefully

Consultation and Safety

Your suitability will be assessed before treatment. This includes your concerns, skin condition, medical history, previous treatments, and expected outcome.

Treatment will only be carried out where it is considered suitable and safe. If polynucleotides are not the right option for you, an alternative treatment or plan may be recommended.